Nota de FísicaPublicado
EPR Evidence for the Existence of a New Hemichrome in Heat Denatured MetHb
O. C. Alves; Eliane Wajnberg
1992
Datos de la publicación
- Autores
- O. C. Alves; Eliane Wajnberg
- Tipo
- Nota de Física
- Estado
- Publicado
- Fecha de publicación
- 1992
- Descripción
- Electron Paramagnetic Resonance was used to follow the time dependence of heat denaturation of met- and nitrosyl-hemoglobin (metHb and HbNO) at 600C, 700C and 800C. The spectral changes of both complexes indicate that conformational changes in the protein manifest themselves in changes of the equilibrium of hemichromes in metHb and of six-and five-coordinated iron in HbNO. The formation of a hemichrome with g = 2.45, 2.27 and 1.85 not described before is observed. A his-Fe-cys complex is proposed for its structure.
- Año
- 1992
- Número
- CBPF-NF-019/92
- Vínculo con tesis
- No
- Vínculo con beca
- No